Although the relevant advances in science, medicine and technology, a definite treatment for cancer is yet to be discovered.  The disease is highly complex and involves several phenomena. Its initiation involves avascular growth. Then, due to an accumulation of cells beyond normal physiological conditions, it occurs hypoxia and acidosis, inducing angiogenesis from the adjacent vasculature. Afterwards, tumour vascularization can occur leading to additional growth, invasion of neighbour tissue and, finally, metastasis. Usually, these events are studied by means of clinical and experimental observations. However, in the recent years, mathematical modelling and computational simulation have complemented the experimental tests, allowing to numerically analyse the problem using multiple time and spatial scales.

Thus, in the recent years, several numerical techniques have appeared to simulate the molecular and cellular biomechanics involved in the computational simulation of cancer. Molecular and cellular biomechanics is an emerging branch of biomechanics that assumes the molecule and the cell as the interest system. This new scientific area starts to be the focus of a large and eclectic scientific community. The daily challenges that arise within the scientific and clinical community act as catalysers for the development of this branch of computational science.

Several computational approaches to predict the molecular and cellular behaviour and interactions (under several academic/clinical perspectives) were developed in the last years to assist cancer research. This never-ending scientific production demands more frequent thematic meetings, in order to allow the update the current state-of-the-art and the exchange of ideas and concepts.

Presently, the modern computer capabilities combined with highly improved numerical approaches allow researchers to predict in-silico the tumour growth with a high level of accuracy. This ECCOMAS thematic conference intends to be a privileged meeting point between research teams, permitting the exchange of ideas and recent progresses on the computational simulation of the molecular/cellular behaviour of tumours and also on the acquired technical and scientific knowledge. One of the main objectives of this ECCOMAS thematic conference is to offer to the participants the opportunity to present their work on the topic. Additionally, this meeting aims to favour the exchange of ideas and knowledge by showing the recently develop scientific concepts and the applied technological advances.

Therefore, this ECCOMAS thematic conference is intended to be a reunion between the most respected experts in the various fields of computational simulation of cancer and to provide an opportunity for updating its state-of-the-art.